24,851 research outputs found

    Measuring attendance: issues and implications for estimating the impact of free-to-view sports events

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    A feature of many non-elite sports events, especially those conducted in public places is that they are free-to-view. The article focuses on the methodological issue of estimating spectator attendance at free-to-view events and the consequences of this for impact evaluation. Using empirical data from three case studies, the article outlines various approaches to measuring attendance and discusses the key issues and implications for evaluating free-to-view sports events in the future

    Cell cycle regulation of a Xenopus Wee1-like kinase

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    Using a polymerase chain reaction-based strategy, we have isolated a gene encoding a Wee1-like kinase from Xenopus eggs. The recombinant Xenopus Wee1 protein efficiently phosphorylates Cdc2 exclusively on Tyr- 15 in a cyclin-dependent manner. The addition of exogenous Wee1 protein to Xenopus cell cycle extracts results in a dose-dependent delay of mitotic initiation that is accompanied by enhanced tyrosine phosphorylation of Cdc2. The activity of the Wee1 protein is highly regulated during the cell cycle: the interphase, underphosphorylated form of Wee1 (68 kDa) phosphorylates Cdc2 very efficiently, whereas the mitotic, hyperphosphorylated version (75 kDa) is weakly active as a Cdc2-specific tyrosine kinase. The down-modulation of Wee1 at mitosis is directly attributable to phosphorylation, since dephosphorylation with protein phosphatase 2A restores its kinase activity. During interphase, the activity of this Wee1 homolog does not vary in response to the presence of unreplicated DNA. The mitosis-specific phosphorylation of Wee1 is due to at least two distinct kinases: the Cdc2 protein and another activity (kinase X) that may correspond to an MPM-2 epitope kinase. These studies indicate that the down-regulation of Wee1-like kinase activity at mitosis is a multistep process that occurs after other biochemical reactions have signaled the successful completion of S phase

    Reply to the comment by Carmelo Anile on the paper "Complexity analysis of the cerebrospinal fluid pulse waveform during infusion studies"

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    Veterinary technology is an emerging profession within the veterinary and allied animal health fields in Australia and affords graduates the opportunity to contribute to the small but growing body of literature within this discipline. This study describes the introduction of a contextualised assessment task to develop students’ research capability, competence and confidence in professional writing, and to engage them with the academic publishing process. Students worked in self-selected dyads to author a scientific case report, of publishable standard, based on authentic cases from their clinical practicum. Intrinsic to the task, students attended a series of workshops that explored topics such as critiquing the literature, professional writing styles and oral presentation skills. Assessment was multi-staged with progressive feedback, including peer review, and culminated with students presenting their abstracts at a mock conference. Students reported the task to be an enjoyable and valuable learning experience which improved their competence and confidence in scientific writing; supported by a comparison of previously submitted work. Linking scientific writing skills to clinical practice experiences enhanced learning outcomes and may foster the professionalisation of students within this emerging discipline

    Smallness of Baryon Asymmetry from Split Supersymmetry

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    The smallness of the baryon asymmetry in our universe is one of the greatest mysteries and may originate from some profound physics beyond the standard model. We investigate the Affleck-Dine baryogenesis in split supersymmetry, and find that the smallness of the baryon asymmetry is directly related to the hierarchy between the supersymmetry breaking squark/slepton masses and the weak scale. Put simply, the baryon asymmetry is small because of the split mass spectrum.Comment: 4 pages, no figur

    Dilution jet mixing program, phase 3

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    The main objectives for the NASA Jet Mixing Phase 3 program were: extension of the data base on the mixing of single sided rows of jets in a confined cross flow to discrete slots, including streamlined, bluff, and angled injections; quantification of the effects of geometrical and flow parameters on penetration and mixing of multiple rows of jets into a confined flow; investigation of in-line, staggered, and dissimilar hole configurations; and development of empirical correlations for predicting temperature distributions for discrete slots and multiple rows of dilution holes

    The Theorem of Jentzsch--Szeg\H{o} on an analytic curve. Application to the irreducibility of truncations of power series

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    The theorem of Jentzsch--Szeg\H{o} describes the limit measure of a sequence of discrete measures associated to the zeroes of a sequence of polynomials in one variable. Following the presentation of this result by Andrievskii and Blatt in their book, we extend this theorem to compact Riemann surfaces, then to analytic curves over an ultrametric field. The particular case of the projective line over an ultrametric field gives as corollaries information about the irreducibility of the truncations of a power series in one variable.Comment: 16 pages; the application to irreducibility and the final example have been correcte

    A system for aerodynamic design and analysis of supersonic aircraft. Part 3: Computer program description

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    The computer program documentation for the design and analysis of supersonic configurations is presented. Schematics and block diagrams of the major program structure, together with subroutine descriptions for each module are included

    Phase 1 of the automated array assembly task of the low cost silicon solar array project

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    The results of a study of process variables and solar cell variables are presented. Interactions between variables and their effects upon control ranges of the variables are identified. The results of a cost analysis for manufacturing solar cells are discussed. The cost analysis includes a sensitivity analysis of a number of cost factors

    Aerodynamic design and analysis system for supersonic aircraft. Part 2: User's manual

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    An integrated system of computer programs for supersonic configurations is described. An explanation of system usage, the input definitions, and example output are included. For Part 1, see N75-18185; for Part 3, see N75-18186
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